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Carol Fabian, MD, has spent nearly 30 years looking for groundbreaking ways to treat or prevent breast cancer. A procedure she developed is now used routinely in breast cancer prevention despite medical colleagues initially scoffing at the idea of randomly sampling breast tissue with a thin needle to detect widespread precancerous changes. Innovative people like Fabian don’t let a little skepticism stop them. She has become one of the foremost breast cancer specialists in the country, garnering numerous accolades for her leadership.

It’s no surprise, then, that Fabian is once again focused on innovation. This time, she is looking for ways to work with breast cancer survivors to make sure they have every advantage for living a life of wellness. In 2007, Fabian, professor of hematology/oncology and director of the Medical Center’s Breast Cancer Prevention Center, will open the Breast Cancer Survivorship Center at the new Westwood Campus of The University of Kansas Hospital. The Survivorship Center, among the first of its kind, will allow Fabian and her colleagues to offer needed services as well as conduct very specific clinical research on how some of these services impact the well-being of breast cancer survivors.

“Many women find it difficult to get back to their pre-breast-cancer life,” Fabian said. “At this center, we’ll be using a collaborative model and structured interventions to help them get there.” The survivors will have access to a range of professionals including a genetic risk counselor, a dietitian, and a clinical psychologist. The initial focus of the Survivorship Center will be on exercise, diet, and weight control. Genetic counseling for breast cancer patients and facilitating access to fertility preservation services for young women with a recent diagnosis also will be offered.

Fabian knows well the community she serves. She grew up in Kansas City and has spent her entire career at the University of Kansas Medical Center. What are some of the advances she’s seen in breast cancer treatment and prevention since she donned her white coat in the mid-1970s? She points to two things that have had a dramatic effect on survival: regular mammograms and the development of better adjuvant (prophylactic) therapy for breast cancer.

“Back when I started out, women diagnosed with breast cancer had about a 50 percent chance for survival. Now, 25 percent or fewer will ultimately die from breast cancer. That’s still too many deaths, but we’re moving in the right direction,” Fabian said.

Fabian focuses much of her energy on exploring measures aimed at prevention. Under her direction, the Breast Cancer Prevention Center serves women who are at high risk for contracting the disease such as women who have a close family member with the disease, women who have dense breast tissue, and those who have had a biopsy indicating pre-cancerous changes.
When they visit the prevention center, the women consult with staff specialists to create a strategy based on their particular indicators and needs. They may also decide to undergo the fine needle aspiration, Fabian’s procedure where cells are drawn from the breast duct and analyzed for changes. This test is performed free of charge. Women may also receive genetic testing and counseling or participate in one of a number of clinical trials as appropriate.

Along with studying the complex biological processes that contribute to breast cancer, Fabian looks at more common elements such as nutrients. For example, she is looking at the effects of Vitamin D on breast cancer risk and prevention. When she tested patients, she was startled to see how many of them demonstrated a deficiency of the vitamin. The best way to get Vitamin D, she says, is by spending 10 to 15 minutes a day in the sun. It also can be found in milk, ocean fish like salmon, and supplements, but in nowhere near the quantities available just by being in the sun.

Barbara Atkinson, MD, executive vice chancellor of the University of Kansas Medical Center and executive dean of the School of Medicine, sees Fabian as a pioneer. “Dr. Fabian sets the pace for helping women with breast cancer overcome the disease and live full, healthy lives. We are extraordinarily fortunate to have someone with her dedication and expertise at the Medical Center.”

But being a pioneer takes time. Fabian’s intense career focus has left little time for hobbies and other outside interests. She tries to keep weekends free to spend time with her family, which now includes a 20-month-old granddaughter, Reese. For Reese and for young girls everywhere, Fabian is doing all she can to make sure they grow into adulthood in a world where breast cancer is no longer a deadly disease – where new therapies and lifestyle habits prevail to better assure the health of women.