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Despite all these avenues for accessing knowledge about our health, inaccurate or conflicting information continues to be spread — whether passed from parent to child, or from Web site to Web site. It can be challenging for even the most wellinformed people to discern between what medical information is credible and what is not.

Our health can depend on our own ability to sort through all of the information and determine what is reliable. To help with that task, we consulted with some of the top doctors and researchers at KU Medical Center to help uncover the truth (or fiction) behind a few commonly held beliefs about medicine and public health.

You can be overweight and healthy.

Fact

Recent studies have suggested that a surprising number of overweight people – about half – have normal blood pressure and cholesterol levels. This is bolstering the argument that you can be hefty and healthy, or at least healthier than has been previously believed.

Christie Befort, PhD, an assistant professor in the Department of Preventive Medicine and Public Health, said research does indicate that physical fitness reduces all-cause, cardiovascular, and diabetesrelated mortality across all body mass index (BMI) categories. But that doesn’t mean overweight and obese people are in the clear if they exercise.

“Being overweight or obese continues to be a large and substantial risk factor for developing Type 2 diabetes and other health problems, even among individuals who meet physical activity recommendations of 30 minutes a day, five days a week,” Dr. Befort said.

The most significant risk factor for breast cancer is having a family history of the disease.

Fiction

It has been estimated that just 5 to 10 percent of all female breast cancer cases are hereditary. They occur as the result of an inherited alteration in a gene. Cancers that arise as a result of these powerful alterations in genes are termed “hereditary” breast cancer. In hereditary breast cancer families, approximately 50 percent of women will be affected, and half of these cancers occur before the age of 50.

“Most often, breast cancer is not a result of change in one of these powerful genes, but rather a complex interplay of changes in weaker genes, a woman’s reproductive history, environmental influences, and lifestyle choices,” said Carol Fabian, MD, director of KU’s Breast Cancer Prevention Center.

If a family member has Alzheimer’s disease, you are more likely to get it, too.

Fact

Familial Alzheimer’s disease (FAD) or early-onset Alzheimer’s is an inherited, rare form of the disease, affecting less than 1 percent of Alzheimer’s disease patients. FAD develops before age 65, in people as young as 35. It is caused by one of three gene mutations on chromosomes 1, 14 and 21. But the majority of Alzheimer’s disease cases are late-onset, usually developing after age 65, said Jeffrey Burns, MD, assistant professor and director of the Alzheimer & Memory Center at KU Medical Center.

“A family history of Alzheimer’s disease might mean your risk is slightly elevated, but it by no means indicates that occurrence of the disease is inevitable,” said Dr. Burns. “Genetic risk factors alone are not enough to cause the late-onset form of Alzheimer’s disease. Researchers are actively exploring education, diet and environment to learn what role they might play in the development of the disease.”