Despite all these avenues for accessing
knowledge about our health, inaccurate
or conflicting information continues to be
spread — whether passed from parent to
child, or from Web site to Web site. It can
be challenging for even the most wellinformed
people to discern between what
medical information is credible and what
is not.
Our health can depend on our own ability
to sort through all of the information and
determine what is reliable. To help with
that task, we consulted with some of the
top doctors and researchers at KU Medical
Center to help uncover the truth (or fiction)
behind a few commonly held beliefs about
medicine and public health.
Fact
Recent studies have suggested that a
surprising number of overweight people –
about half – have normal blood pressure
and cholesterol levels. This is bolstering
the argument that you can be hefty and
healthy, or at least healthier than has been
previously believed.
Christie Befort, PhD, an assistant professor
in the Department of Preventive Medicine
and Public Health, said research does
indicate that physical fitness reduces
all-cause, cardiovascular, and diabetesrelated
mortality across all body mass
index (BMI) categories. But that doesn’t
mean overweight and obese people are in
the clear if they exercise.
“Being overweight or obese continues
to be a large and substantial risk factor
for developing Type 2 diabetes and other
health problems, even among individuals
who meet physical activity recommendations
of 30 minutes a day, five days a week,”
Dr. Befort said.
Fiction
It has been estimated that just 5 to 10
percent of all female breast cancer cases
are hereditary. They occur as the result
of an inherited alteration in a gene.
Cancers that arise as a result of these
powerful alterations in genes are termed
“hereditary” breast cancer. In hereditary
breast cancer families, approximately 50
percent of women will be affected, and
half of these cancers occur before the age
of 50.
“Most often, breast cancer is not a result
of change in one of these powerful
genes, but rather a complex interplay of
changes in weaker genes, a woman’s
reproductive history, environmental
influences, and lifestyle choices,” said
Carol Fabian, MD, director of KU’s Breast
Cancer Prevention Center.
Fact
Familial Alzheimer’s disease (FAD) or
early-onset Alzheimer’s is an inherited,
rare form of the disease, affecting less than
1 percent of Alzheimer’s disease patients.
FAD develops before age 65, in people as
young as 35. It is caused by one of three
gene mutations on chromosomes 1, 14
and 21. But the majority of Alzheimer’s
disease cases are late-onset, usually
developing after age 65, said Jeffrey Burns,
MD, assistant professor and director of
the Alzheimer & Memory Center at KU
Medical Center.
“A family history of Alzheimer’s disease
might mean your risk is slightly elevated,
but it by no means indicates that
occurrence of the disease is inevitable,”
said Dr. Burns. “Genetic risk factors alone
are not enough to cause the late-onset
form of Alzheimer’s disease. Researchers
are actively exploring education, diet and
environment to learn what role they might
play in the development of the disease.”